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Cortisol is a steroid hormone that regulates a vertebrate animal’s… Cortisol is a steroid hormone that regulates a vertebrate animal’s response to stress and inhibits inflammation. Agonists similar to cortisol are usedmedically to reduce symptoms of certain inflammatory disorders. Stress stimulates the sympathetic nervous system to initiate the secretion of corticotropin-releasing hormone (CRH). CRH is a signal peptide synthesized and released from CRH neurons in the hypothalamus. CRH stimulates adrenccorticotropic (ACTH) hormone release from the anterior pituitary gland, which activates cortisol release from the adrenal glands. Neurons that release CRIH contain cortisol receptors that are under negative feedback control. Use this information to answer the questions below.1. A mutation that reduces the amount of cortisol released by the adrenal glands would decrease CRH synthesis.TRUE OR FALSE2. A fluorescent marker can be used to selectively label cortisol receptors.True or False: The fluorescent marker will be localized at the plasma membrane of cells in the hypothalamus.3. A loss-of function mutation in kinesin results in a build up of secretory vesicles containing CRH in the axon terminals of neurons,TRUE OR FALSEBiology Science cell biology LIFESCIENC 7C

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